BAIT
ANKRD1
ALRP, C-193, CARP, CVARP, MCARP, bA320F15.2
ankyrin repeat domain 1 (cardiac muscle)
GO Process (15)
GO Function (9)
GO Component (7)
Gene Ontology Biological Process
- cardiac muscle tissue morphogenesis [IMP]
- cellular lipid metabolic process [TAS]
- cellular response to interleukin-1 [IDA]
- cellular response to lipopolysaccharide [IDA]
- cellular response to mechanical stimulus [IDA]
- cellular response to transforming growth factor beta stimulus [IDA]
- cellular response to tumor necrosis factor [IDA]
- negative regulation of DNA biosynthetic process [IMP]
- positive regulation of DNA damage response, signal transduction by p53 class mediator [IDA]
- positive regulation of apoptotic process [IMP]
- positive regulation of protein secretion [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- response to muscle stretch [IMP]
- sarcomere organization [NAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Homo sapiens
PREY
LRPPRC
CLONE-23970, GP130, LRP130, LSFC
leucine-rich pentatricopeptide repeat containing
GO Process (1)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.
The complexity of the skeletal muscle and the identification of numerous human disease-causing mutations in its constitutive proteins make it an interesting tissue for proteomic studies aimed at understanding functional relationships of interacting proteins in both health and diseases.We undertook a large-scale study using two-hybrid screens and a human skeletal-muscle cDNA library to establish a proteome-scale map of protein-protein interactions ... [more]
Skelet Muscle Feb. 19, 2013; 3(1);3 [Pubmed: 23414517]
Throughput
- High Throughput
Curated By
- BioGRID