BAIT
ANKRD28
PITK, PPP1R65
ankyrin repeat domain 28
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
PREY
BCL3
BCL4, D19S37
B-cell CLL/lymphoma 3
GO Process (17)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
- DNA damage response, signal transduction by p53 class mediator [IMP]
- I-kappaB kinase/NF-kappaB signaling [IDA]
- cellular response to DNA damage stimulus [IDA]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IMP]
- maintenance of protein location in nucleus [NAS]
- negative regulation of apoptotic process [IDA]
- negative regulation of interleukin-8 biosynthetic process [IMP]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- positive regulation of translation [IMP]
- protein import into nucleus, translocation [IMP]
- regulation of DNA binding [IEP]
- regulation of NF-kappaB import into nucleus [IEP]
- regulation of apoptotic process [IDA]
- response to UV-C [IDA]
- response to virus [IDA]
- transcription, DNA-templated [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.
The complexity of the skeletal muscle and the identification of numerous human disease-causing mutations in its constitutive proteins make it an interesting tissue for proteomic studies aimed at understanding functional relationships of interacting proteins in both health and diseases.We undertook a large-scale study using two-hybrid screens and a human skeletal-muscle cDNA library to establish a proteome-scale map of protein-protein interactions ... [more]
Skelet Muscle Feb. 19, 2013; 3(1);3 [Pubmed: 23414517]
Throughput
- High Throughput
Curated By
- BioGRID