BAIT
APPL1
APPL, DIP13alpha
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
GO Process (8)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
- apoptotic process [TAS]
- cell proliferation [IDA]
- insulin receptor signaling pathway [TAS]
- positive regulation of apoptotic process [TAS]
- regulation of apoptotic process [TAS]
- regulation of establishment of protein localization to plasma membrane [IMP]
- regulation of glucose import [IMP]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
BIN1
AMPH2, AMPHL, SH3P9
bridging integrator 1
GO Process (6)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.
The complexity of the skeletal muscle and the identification of numerous human disease-causing mutations in its constitutive proteins make it an interesting tissue for proteomic studies aimed at understanding functional relationships of interacting proteins in both health and diseases.We undertook a large-scale study using two-hybrid screens and a human skeletal-muscle cDNA library to establish a proteome-scale map of protein-protein interactions ... [more]
Skelet Muscle Feb. 19, 2013; 3(1);3 [Pubmed: 23414517]
Throughput
- High Throughput
Curated By
- BioGRID