BAIT
DNAJB6
DJ4, DnaJ, HHDJ1, HSJ-2, HSJ2, LGMD1D, LGMD1E, MRJ, MSJ-1, tcag7.555
DnaJ (Hsp40) homolog, subfamily B, member 6
GO Process (5)
GO Function (5)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
SUPT6H
SPT6, SPT6H, emb-5
suppressor of Ty 6 homolog (S. cerevisiae)
GO Process (8)
GO Function (4)
GO Component (1)
Gene Ontology Biological Process
- chromatin remodeling [NAS]
- negative regulation of histone H3-K27 methylation [IMP]
- positive regulation of transcription elongation from RNA polymerase II promoter [IMP]
- regulation of isotype switching [ISS]
- regulation of mRNA export from nucleus [ISS]
- regulation of mRNA processing [ISS]
- regulation of muscle cell differentiation [ISS]
- regulation of transcription, DNA-templated [NAS]
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.
The complexity of the skeletal muscle and the identification of numerous human disease-causing mutations in its constitutive proteins make it an interesting tissue for proteomic studies aimed at understanding functional relationships of interacting proteins in both health and diseases.We undertook a large-scale study using two-hybrid screens and a human skeletal-muscle cDNA library to establish a proteome-scale map of protein-protein interactions ... [more]
Skelet Muscle Feb. 19, 2013; 3(1);3 [Pubmed: 23414517]
Throughput
- High Throughput
Curated By
- BioGRID