BAIT
DYSF
FER1L1, LGMD2B, MMD1
dysferlin
GO Process (0)
GO Function (4)
GO Component (8)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
NPHP3
CFAP31, MKS7, NPH3, RHPD, RHPD1, SLSN3
nephronophthisis 3 (adolescent)
GO Process (19)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- atrial septum development [IMP]
- cilium morphogenesis [ISS]
- convergent extension involved in gastrulation [IGI]
- determination of intestine left/right asymmetry [IMP]
- determination of left/right symmetry [IMP]
- determination of liver left/right asymmetry [IMP]
- determination of pancreatic left/right asymmetry [IMP]
- determination of stomach left/right asymmetry [IMP]
- epithelial cilium movement involved in determination of left/right asymmetry [IC]
- heart looping [IMP]
- kidney development [IMP]
- kidney morphogenesis [IMP]
- lung development [IMP]
- maintenance of organ identity [IMP]
- negative regulation of canonical Wnt signaling pathway [IDA]
- photoreceptor cell maintenance [IMP]
- regulation of Wnt signaling pathway, planar cell polarity pathway [ISS]
- regulation of planar cell polarity pathway involved in neural tube closure [IC]
- ureter development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.
The complexity of the skeletal muscle and the identification of numerous human disease-causing mutations in its constitutive proteins make it an interesting tissue for proteomic studies aimed at understanding functional relationships of interacting proteins in both health and diseases.We undertook a large-scale study using two-hybrid screens and a human skeletal-muscle cDNA library to establish a proteome-scale map of protein-protein interactions ... [more]
Skelet Muscle Feb. 19, 2013; 3(1);3 [Pubmed: 23414517]
Throughput
- High Throughput
Curated By
- BioGRID