FHL1
Gene Ontology Biological Process
- muscle organ development [NAS]
- negative regulation of G1/S transition of mitotic cell cycle [IDA]
- negative regulation of G2/M transition of mitotic cell cycle [IDA]
- negative regulation of cell growth [IDA]
- organ morphogenesis [NAS]
- positive regulation of potassium ion transport [IDA]
- regulation of membrane depolarization [IDA]
- regulation of potassium ion transmembrane transporter activity [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
AKAP12
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.
The complexity of the skeletal muscle and the identification of numerous human disease-causing mutations in its constitutive proteins make it an interesting tissue for proteomic studies aimed at understanding functional relationships of interacting proteins in both health and diseases.We undertook a large-scale study using two-hybrid screens and a human skeletal-muscle cDNA library to establish a proteome-scale map of protein-protein interactions ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
AKAP12 FHL1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 3347676 | |
FHL1 AKAP12 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |
Curated By
- BioGRID