BAIT
PYGM
phosphorylase, glycogen, muscle
GO Process (5)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
IGBP1
ALPHA-4, IBP1, RP13-46G5.1
immunoglobulin (CD79A) binding protein 1
GO Process (7)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- negative regulation of stress-activated MAPK cascade [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- regulation of microtubule-based movement [IMP]
- response to interleukin-1 [IMP]
- response to tumor necrosis factor [IMP]
- signal transduction [NAS]
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.
The complexity of the skeletal muscle and the identification of numerous human disease-causing mutations in its constitutive proteins make it an interesting tissue for proteomic studies aimed at understanding functional relationships of interacting proteins in both health and diseases.We undertook a large-scale study using two-hybrid screens and a human skeletal-muscle cDNA library to establish a proteome-scale map of protein-protein interactions ... [more]
Skelet Muscle Feb. 19, 2013; 3(1);3 [Pubmed: 23414517]
Throughput
- High Throughput
Curated By
- BioGRID