BAIT
TCAP
CMD1N, LGMD2G, T-cap, TELE, telethonin
titin-cap
GO Process (17)
GO Function (8)
GO Component (3)
Gene Ontology Biological Process
- adult heart development [IMP]
- cardiac muscle contraction [IMP]
- cardiac muscle fiber development [IMP]
- cardiac muscle hypertrophy [IMP]
- cardiac muscle hypertrophy in response to stress [IMP]
- cardiac muscle tissue morphogenesis [IMP]
- cardiac myofibril assembly [IMP]
- detection of mechanical stimulus [TAS]
- detection of muscle stretch [IMP]
- muscle filament sliding [TAS]
- protein complex assembly [TAS]
- response to muscle stretch [TAS]
- sarcomere organization [IMP, TAS]
- sarcomerogenesis [IMP]
- skeletal muscle contraction [IEP]
- skeletal muscle myosin thick filament assembly [IMP]
- skeletal muscle thin filament assembly [IMP]
Gene Ontology Molecular Function
Homo sapiens
PREY
ENO3
GSD13, MSE
enolase 3 (beta, muscle)
GO Process (5)
GO Function (0)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.
The complexity of the skeletal muscle and the identification of numerous human disease-causing mutations in its constitutive proteins make it an interesting tissue for proteomic studies aimed at understanding functional relationships of interacting proteins in both health and diseases.We undertook a large-scale study using two-hybrid screens and a human skeletal-muscle cDNA library to establish a proteome-scale map of protein-protein interactions ... [more]
Skelet Muscle Feb. 19, 2013; 3(1);3 [Pubmed: 23414517]
Throughput
- High Throughput
Curated By
- BioGRID