BAIT
DDX1
DBP-RB, UKVH5d
DEAD (Asp-Glu-Ala-Asp) box helicase 1
GO Process (8)
GO Function (9)
GO Component (8)
Gene Ontology Biological Process
- ATP catabolic process [IDA]
- DNA duplex unwinding [IDA]
- double-strand break repair [IDA]
- multicellular organismal development [IEP]
- nucleic acid phosphodiester bond hydrolysis [IDA]
- regulation of translational initiation [NAS]
- spliceosomal complex assembly [NAS]
- tRNA splicing, via endonucleolytic cleavage and ligation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
LMAN1
ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58
lectin, mannose-binding, 1
GO Process (10)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- ER to Golgi vesicle-mediated transport [TAS]
- Golgi organization [IMP]
- blood coagulation [TAS]
- cellular protein metabolic process [TAS]
- early endosome to Golgi transport [IMP]
- positive regulation of organelle organization [IMP]
- post-translational protein modification [TAS]
- protein N-linked glycosylation via asparagine [TAS]
- protein exit from endoplasmic reticulum [IMP]
- protein folding [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.
mRNA processing, transport, translation, and ultimately degradation involve a series of dedicated protein complexes that often assemble into large membraneless structures such as stress granules (SGs) and processing bodies (PBs). Here, systematic in vivo proximity-dependent biotinylation (BioID) analysis of 119 human proteins associated with different aspects of mRNA biology uncovers 7424 unique proximity interactions with 1,792 proteins. Classical bait-prey analysis reveals ... [more]
Mol. Cell Dec. 01, 2017; 69(3);517-532.e11 [Pubmed: 29395067]
Throughput
- High Throughput
Additional Notes
- BioID
- High confidence interactions had a SAINTexpress score or AvgP >= 0.95.
Curated By
- BioGRID