BAIT
FXR2
FMR1L2, FXR2P
fragile X mental retardation, autosomal homolog 2
GO Process (1)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
ANKRD17
GTAR, NY-BR-16
ankyrin repeat domain 17
GO Process (8)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- defense response to bacterium [IDA]
- innate immune response [IDA]
- positive regulation of G1/S transition of mitotic cell cycle [IMP]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IDA]
- positive regulation of MDA-5 signaling pathway [IDA]
- positive regulation of RIG-I signaling pathway [IDA]
- positive regulation of cell cycle [IMP]
- regulation of DNA replication [IMP]
Gene Ontology Molecular Function
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.
mRNA processing, transport, translation, and ultimately degradation involve a series of dedicated protein complexes that often assemble into large membraneless structures such as stress granules (SGs) and processing bodies (PBs). Here, systematic in vivo proximity-dependent biotinylation (BioID) analysis of 119 human proteins associated with different aspects of mRNA biology uncovers 7424 unique proximity interactions with 1,792 proteins. Classical bait-prey analysis reveals ... [more]
Mol. Cell Dec. 01, 2017; 69(3);517-532.e11 [Pubmed: 29395067]
Throughput
- High Throughput
Additional Notes
- BioID
- High confidence interactions had a SAINTexpress score or AvgP >= 0.95.
Curated By
- BioGRID