LSM2
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- RNA splicing [TAS]
- exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- mRNA splicing, via spliceosome [IC, TAS]
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
LSM1
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- RNA splicing [TAS]
- RNA splicing, via transesterification reactions [TAS]
- deadenylation-dependent decapping of nuclear-transcribed mRNA [IBA]
- exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [TAS]
- gene expression [TAS]
- histone mRNA catabolic process [IMP]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [TAS]
Gene Ontology Molecular Function
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.
mRNA processing, transport, translation, and ultimately degradation involve a series of dedicated protein complexes that often assemble into large membraneless structures such as stress granules (SGs) and processing bodies (PBs). Here, systematic in vivo proximity-dependent biotinylation (BioID) analysis of 119 human proteins associated with different aspects of mRNA biology uncovers 7424 unique proximity interactions with 1,792 proteins. Classical bait-prey analysis reveals ... [more]
Throughput
- High Throughput
Additional Notes
- BioID
- High confidence interactions had a SAINTexpress score or AvgP >= 0.95.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| LSM1 LSM2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9999 | BioGRID | 3101254 | |
| LSM2 LSM1 | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | High | 1 | BioGRID | 1264185 | |
| LSM1 LSM2 | Proximity Label-MS Proximity Label-MS An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods. | High | - | BioGRID | 2814615 | |
| LSM1 LSM2 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - | |
| LSM2 LSM1 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - | |
| LSM1 LSM2 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | 2741095 |
Curated By
- BioGRID