BAIT
ST7
ETS7q, FAM4A, FAM4A1, HELG, RAY1, SEN4, TSG7
suppression of tumorigenicity 7
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
ANO6
BDPLT7, SCTS, TMEM16F
anoctamin 6
GO Process (12)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
- activation of blood coagulation via clotting cascade [IMP]
- blood coagulation [ISS]
- cation transmembrane transport [IDA, ISS]
- cation transport [IDA]
- chloride transmembrane transport [IMP]
- chloride transport [IMP]
- ion transmembrane transport [TAS]
- phosphatidylserine exposure on blood platelet [IMP]
- phospholipid scrambling [ISS]
- positive regulation of endothelial cell apoptotic process [IMP]
- regulation of anion transport [IMP]
- transmembrane transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.
mRNA processing, transport, translation, and ultimately degradation involve a series of dedicated protein complexes that often assemble into large membraneless structures such as stress granules (SGs) and processing bodies (PBs). Here, systematic in vivo proximity-dependent biotinylation (BioID) analysis of 119 human proteins associated with different aspects of mRNA biology uncovers 7424 unique proximity interactions with 1,792 proteins. Classical bait-prey analysis reveals ... [more]
Mol. Cell Dec. 01, 2017; 69(3);517-532.e11 [Pubmed: 29395067]
Throughput
- Low Throughput
Additional Notes
- BioID
- High confidence interactions had a SAINTexpress score or AvgP >= 0.95.
Curated By
- BioGRID