RHOQ
Gene Ontology Biological Process
- GTP catabolic process [IDA]
- cellular response to insulin stimulus [IMP]
- cortical actin cytoskeleton organization [IMP]
- insulin receptor signaling pathway [IMP]
- negative regulation of establishment of protein localization to plasma membrane [IMP]
- positive regulation of filopodium assembly [IDA]
- positive regulation of glucose import [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of actin cytoskeleton organization [IC]
- regulation of small GTPase mediated signal transduction [TAS]
- small GTPase mediated signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
GOPC
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
PIST: a novel PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10.
TC10 is a member of the Rho family of GTPases, most closely related to Cdc42. This family of proteins mediates cytoskeletal rearrangements, activation of signal transduction cascades, and activation of gene transcription. A current focus is to identify and characterize the GTPase effectors that are involved in these cellular events. Many specific effectors for Cdc42 have been identified, most of ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| GOPC RHOQ | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - | |
| RHOQ GOPC | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |
Curated By
- BioGRID