BAIT
ELAVL1
ELAV1, HUR, Hua, MelG
ELAV like RNA binding protein 1
GO Process (8)
GO Function (9)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
ZNF703
ZEPPO1, ZNF503L, ZPO1
zinc finger protein 703
GO Process (13)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
- adherens junction assembly [ISS]
- cellular response to estradiol stimulus [IDA]
- mammary gland epithelial cell differentiation [IDA]
- negative regulation of homotypic cell-cell adhesion [ISS]
- negative regulation of transcription, DNA-templated [IMP]
- positive regulation of cell migration [ISS]
- positive regulation of cell proliferation [IDA]
- positive regulation of epithelial to mesenchymal transition [ISS]
- positive regulation of mammary gland epithelial cell proliferation [IDA]
- regulation of canonical Wnt signaling pathway [ISS]
- regulation of cell cycle [IDA]
- regulation of transcription, DNA-templated [IDA]
- regulation of transforming growth factor beta receptor signaling pathway [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.
mRNA processing, transport, translation, and ultimately degradation involve a series of dedicated protein complexes that often assemble into large membraneless structures such as stress granules (SGs) and processing bodies (PBs). Here, systematic in vivo proximity-dependent biotinylation (BioID) analysis of 119 human proteins associated with different aspects of mRNA biology uncovers 7424 unique proximity interactions with 1,792 proteins. Classical bait-prey analysis reveals ... [more]
Mol. Cell Dec. 01, 2017; 69(3);517-532.e11 [Pubmed: 29395067]
Throughput
- Low Throughput
Additional Notes
- BioID
- High confidence interactions had a SAINTexpress score or AvgP >= 0.95.
Curated By
- BioGRID