BAIT
PPP1CA
PP-1A, PP1A, PP1alpha, PPP1A
protein phosphatase 1, catalytic subunit, alpha isozyme
GO Process (8)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
- circadian regulation of gene expression [ISS]
- entrainment of circadian clock by photoperiod [ISS]
- negative regulation of transforming growth factor beta receptor signaling pathway [TAS]
- protein dephosphorylation [IMP, ISS]
- regulation of circadian rhythm [IMP]
- small molecule metabolic process [TAS]
- transforming growth factor beta receptor signaling pathway [TAS]
- triglyceride catabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
NOC2L
NET15, NET7, NIR, PPP1R112
nucleolar complex associated 2 homolog (S. cerevisiae)
GO Process (7)
GO Function (7)
GO Component (3)
Gene Ontology Biological Process
- cellular response to UV [IDA]
- chromatin assembly [IDA]
- negative regulation of B cell apoptotic process [IMP]
- negative regulation of histone acetylation [IDA]
- negative regulation of intrinsic apoptotic signaling pathway [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- nucleolus to nucleoplasm transport [IDA]
Gene Ontology Molecular Function
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Association of a protein phosphatase 1 activity with the human factor C1 (HCF) complex.
We have screened a human cDNA expression library with a digoxygenin-labelled protein phosphatase 1 (PP1) probe to identify novel PP1 interacting proteins. Eleven cDNA clones were isolated, which included genes encoding two previously characterised and six novel PP1 binding proteins. Three of the cDNAs encoded a protein called host cell factor (HCF), which is an essential component of the cellular ... [more]
Nucleic Acids Res. Feb. 01, 2000; 28(3);678-86 [Pubmed: 10637318]
Throughput
- Low Throughput
Curated By
- BioGRID