BAIT
EXOSC10
PM-Scl, PM/Scl-100, PMSCL, PMSCL2, RRP6, Rrp6p, p2, p3, p4
exosome component 10
GO Process (9)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
- CUT catabolic process [IMP]
- RNA phosphodiester bond hydrolysis, exonucleolytic [IDA]
- histone mRNA catabolic process [IMP]
- maturation of 5.8S rRNA [IMP]
- nuclear mRNA surveillance [IMP]
- nuclear polyadenylation-dependent rRNA catabolic process [IMP]
- nuclear retention of unspliced pre-mRNA at the site of transcription [IMP]
- nuclear-transcribed mRNA catabolic process [IMP]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TXNL1
HEL-S-114, TRP32, TXL-1, TXNL, Txl
thioredoxin-like 1
GO Process (0)
GO Function (1)
GO Component (2)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.
mRNA processing, transport, translation, and ultimately degradation involve a series of dedicated protein complexes that often assemble into large membraneless structures such as stress granules (SGs) and processing bodies (PBs). Here, systematic in vivo proximity-dependent biotinylation (BioID) analysis of 119 human proteins associated with different aspects of mRNA biology uncovers 7424 unique proximity interactions with 1,792 proteins. Classical bait-prey analysis reveals ... [more]
Mol. Cell Dec. 01, 2017; 69(3);517-532.e11 [Pubmed: 29395067]
Throughput
- Low Throughput
Additional Notes
- BioID
- High confidence interactions had a SAINTexpress score or AvgP >= 0.95.
Curated By
- BioGRID