BAIT
NEK4
NRK2, STK2, pp12301
NIMA-related kinase 4
GO Process (7)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
TRIO
ARHGEF23, tgat
trio Rho guanine nucleotide exchange factor
GO Process (8)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
- apoptotic signaling pathway [TAS]
- axon guidance [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of GTPase activity [TAS]
- positive regulation of apoptotic process [TAS]
- regulation of small GTPase mediated signal transduction [TAS]
- small GTPase mediated signal transduction [TAS]
- transmembrane receptor protein tyrosine phosphatase signaling pathway [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.
Neks are serine-threonine kinases that are similar to NIMA, a protein found in Aspergillus nidulans which is essential for cell division. In humans there are eleven Neks which are involved in different biological functions besides the cell cycle control. Nek4 is one of the largest members of the Nek family and has been related to the primary cilia formation and ... [more]
Unknown Mar. 24, 2015; 13();11 [Pubmed: 25798074]
Throughput
- High Throughput
Curated By
- BioGRID