BAIT
DCC
CRC18, CRCR1, IGDCC1, MRMV1, NTN1R1
DCC netrin 1 receptor
GO Process (9)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- apoptotic process [TAS]
- axon guidance [TAS]
- axonogenesis [TAS]
- negative regulation of collateral sprouting [TAS]
- negative regulation of dendrite development [TAS]
- negative regulation of neuron projection development [TAS]
- positive regulation of apoptotic process [TAS]
- regulation of apoptotic process [TAS]
- regulation of neuron death [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ALDOB
ALDB, ALDO2, RP11-490D19.1
aldolase B, fructose-bisphosphate
GO Process (11)
GO Function (7)
GO Component (4)
Gene Ontology Biological Process
- NADH oxidation [IDA]
- carbohydrate metabolic process [TAS]
- fructose 1,6-bisphosphate metabolic process [IDA]
- fructose catabolic process [TAS]
- fructose metabolic process [IMP]
- gluconeogenesis [TAS]
- glucose metabolic process [TAS]
- glycolytic process [IDA, TAS]
- positive regulation of ATPase activity [IGI]
- small molecule metabolic process [TAS]
- vacuolar proton-transporting V-type ATPase complex assembly [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Charting the molecular links between driver and susceptibility genes in colorectal cancer.
Despite significant advances in the identification of specific genes and pathways important in the onset and progression of colorectal cancer (CRC), mechanistic insight into the relationship between driver and susceptibility genes is needed. In this paper, we systematically explore physical interactions between causative and putative CRC susceptibility genes to reveal the molecular mechanisms involved in tumor biology. In total, we ... [more]
Unknown Mar. 21, 2014; 445(4);734-8 [Pubmed: 24412244]
Throughput
- High Throughput
Curated By
- BioGRID