BAIT
MLH1
COCA2, FCC2, HNPCC, HNPCC2, hMLH1
mutL homolog 1
GO Process (3)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
STX17
syntaxin 17
GO Process (8)
GO Function (3)
GO Component (12)
Gene Ontology Biological Process
- ER to Golgi vesicle-mediated transport [IMP]
- Golgi organization [IMP]
- autophagic vacuole fusion [IMP]
- endoplasmic reticulum-Golgi intermediate compartment organization [IMP]
- intracellular protein transport [IBA]
- protein localization to pre-autophagosomal structure [IDA]
- vesicle docking [IBA]
- vesicle fusion [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- ER to Golgi transport vesicle [ISS]
- ER-mitochondrion membrane contact site [IDA]
- SNARE complex [IDA]
- autophagic vacuole membrane [IDA]
- cytosol [ISS]
- endoplasmic reticulum membrane [IDA]
- endoplasmic reticulum-Golgi intermediate compartment [IDA]
- integral component of membrane [IBA]
- lysosomal membrane [IDA]
- mitochondrion [IDA]
- rough endoplasmic reticulum [IDA]
- smooth endoplasmic reticulum membrane [ISS]
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Charting the molecular links between driver and susceptibility genes in colorectal cancer.
Despite significant advances in the identification of specific genes and pathways important in the onset and progression of colorectal cancer (CRC), mechanistic insight into the relationship between driver and susceptibility genes is needed. In this paper, we systematically explore physical interactions between causative and putative CRC susceptibility genes to reveal the molecular mechanisms involved in tumor biology. In total, we ... [more]
Unknown Mar. 21, 2014; 445(4);734-8 [Pubmed: 24412244]
Throughput
- High Throughput
Curated By
- BioGRID