BAIT

EIF3C

EIF3CL, EIF3S8, eIF3-p110
eukaryotic translation initiation factor 3, subunit C
GO Process (4)
GO Function (3)
GO Component (2)
Homo sapiens
PREY

EIF3J

EIF3S1, eIF3-alpha, eIF3-p35, PRO0391
eukaryotic translation initiation factor 3, subunit J
GO Process (5)
GO Function (2)
GO Component (2)
Homo sapiens

Co-purification

An interaction is inferred from the identification of two or more protein subunits in a purified protein complex, as obtained by classical biochemical fractionation or affinity purification and one or more additional fractionation steps.

Publication

Changes in ribosomal binding activity of eIF3 correlate with increased translation rates during activation of T lymphocytes.

Miyamoto S, Patel P, Hershey JW

The rate of protein synthesis in quiescent peripheral blood T lymphocytes increases dramatically following mitogenic activation. The stimulation of translation is due to an increase in the rate of initiation caused by the regulation of initiation factor activities. Here, we focus on eIF3, a large multiprotein complex that plays a central role in the formation of the 40 S initiation ... [more]

J. Biol. Chem. Aug. 05, 2005; 280(31);28251-64 [Pubmed: 15946946]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
EIF3J EIF3C
Co-fractionation
Co-fractionation

Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

High-BioGRID
3433573

Curated By

  • BioGRID