BAIT
PLG
RP1-81D8.1
plasminogen
GO Process (12)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
- blood coagulation [IMP, TAS]
- cellular protein metabolic process [TAS]
- extracellular matrix disassembly [IDA, TAS]
- extracellular matrix organization [TAS]
- fibrinolysis [TAS]
- negative regulation of cell proliferation [TAS]
- negative regulation of cell-cell adhesion mediated by cadherin [TAS]
- negative regulation of cell-substrate adhesion [IDA]
- negative regulation of fibrinolysis [IDA]
- platelet activation [TAS]
- platelet degranulation [TAS]
- positive regulation of fibrinolysis [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
S100A10
42C, ANX2L, ANX2LG, CAL1L, CLP11, Ca[1], GP11, P11, p10
S100 calcium binding protein A10
GO Process (8)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
- establishment of protein localization to plasma membrane [IDA]
- membrane budding [IDA]
- membrane raft assembly [IDA]
- positive regulation of Rac GTPase activity [IMP]
- positive regulation of focal adhesion assembly [IMP]
- positive regulation of stress fiber assembly [IMP]
- positive regulation of substrate adhesion-dependent cell spreading [IMP]
- protein heterotetramerization [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Far Western
An interaction is detected between a protein immobilized on a membrane and a purified protein probe.
Publication
The p11 subunit of annexin II heterotetramer is regulated by basic carboxypeptidase.
The Ca(2+)-dependent phospholipid-binding protein annexin II heterotetramer (AIIt) is composed of two copies of annexin II and a p11 dimer. The interaction of the carboxyl-terminal lysine residues of the p11 subunit of AIIt with the lysine-binding kringle domains of plasminogen is believed to play a key role in plasminogen binding and stimulation of the tPA-catalyzed cleavage of plasminogen to plasmin. ... [more]
Biochemistry Apr. 16, 2002; 41(15);4953-61 [Pubmed: 11939791]
Throughput
- Low Throughput
Curated By
- BioGRID