BAIT

STON2

STN2, STNB, STNB2
stonin 2
GO Process (2)
GO Function (1)
GO Component (2)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

EPS15L1

EPS15R
epidermal growth factor receptor pathway substrate 15-like 1
GO Process (2)
GO Function (1)
GO Component (2)
Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Stonin 2: an adaptor-like protein that interacts with components of the endocytic machinery.

Martina JA, Bonangelino CJ, Aguilar RC, Bonifacino JS

Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. Here, we report the identification of two ubiquitously expressed human proteins, stonin 1 and stonin 2, related to components of the endocytic machinery. The human stonins are homologous to the Drosophila melanogaster stoned B protein and exhibit a ... [more]

J. Cell Biol. May. 28, 2001; 153(5);1111-20 [Pubmed: 11381094]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
EPS15L1 STON2
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

High1BioGRID
3095170

Curated By

  • BioGRID