BAIT

ZMYND8

PRKCBP1, PRO2893, RACK7, RP5-890O15.1
zinc finger, MYND-type containing 8
GO Process (1)
GO Function (3)
GO Component (1)
Homo sapiens
PREY

FHOD1

FHOS
formin homology 2 domain containing 1
GO Process (2)
GO Function (2)
GO Component (4)
Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Identification of FHOD1-binding proteins and mechanisms of FHOD1-regulated actin dynamics.

Westendorf JJ, Koka S

Formin homology-2-domain containing protein 1 (FHOD1) regulates gene transcription, actin-cytoskeleton structure, and cell migration. To gain insight into the mechanisms by which FHOD1 mediates these diverse activities, a yeast-two-hybrid screen was performed to identify FHOD1-binding proteins. Three proteins specifically interacted with the carboxy-terminal two-thirds of FHOD1, which includes the FH1, FH2, and diaphanous activating domains (DAD). The newly identified FHOD1-binding ... [more]

J. Cell. Biochem. May. 01, 2004; 92(1);29-41 [Pubmed: 15095401]

Throughput

  • Low Throughput

Curated By

  • BioGRID