BAIT
UBASH3A
CLIP4, STS-2, TULA, TULA-1
ubiquitin associated and SH3 domain containing A
GO Process (0)
GO Function (0)
GO Component (2)
Gene Ontology Cellular Component
Homo sapiens
PREY
HSPA6
heat shock 70kDa protein 6 (HSP70B')
GO Process (5)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
UBASH3A Regulates the Synthesis and Dynamics of TCR-CD3 Complexes.
The TCR-CD3 complex is a multicomponent membrane receptor, the expression of which is tightly regulated in thymocytes, as well as in mature T cells both at steady state and upon stimulation. In this study, we report novel roles for UBASH3A in TCR-CD3 synthesis and turnover. UBASH3A is a negative regulator of T cell function and plays a broad role in ... [more]
J Immunol Dec. 01, 2018; 203(11);2827-2836 [Pubmed: 31659016]
Throughput
- High Throughput
Curated By
- BioGRID