BAIT
LSM1
CASM, YJL124C
LSM1, U6 small nuclear RNA associated
GO Process (9)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- RNA splicing [TAS]
- RNA splicing, via transesterification reactions [TAS]
- deadenylation-dependent decapping of nuclear-transcribed mRNA [IBA]
- exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [TAS]
- gene expression [TAS]
- histone mRNA catabolic process [IMP]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [TAS]
Gene Ontology Molecular Function
Homo sapiens
PREY
VPS11
END1, PEP5, RNF108, hVPS11, PP3476
vacuolar protein sorting 11 homolog (S. cerevisiae)
GO Process (0)
GO Function (2)
GO Component (6)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction framework for human mRNA degradation.
The degradation of mRNA is an important regulatory step in the control of gene expression. However, mammalian RNA decay pathways remain poorly characterized. To provide a framework for studying mammalian RNA decay, a two-hybrid protein interaction map was generated using 54 constructs from 38 human proteins predicted to function in mRNA decay. The results provide evidence for interactions between many ... [more]
Genome Res. Jul. 01, 2004; 14(7);1315-23 [Pubmed: 15231747]
Throughput
- High Throughput
Curated By
- BioGRID