BAIT
LSM3
SMX4, USS2, YLR438C, MDS017
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
GO Process (7)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- mRNA processing [TAS]
- mRNA splicing, via spliceosome [IC]
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [TAS]
Gene Ontology Molecular Function
Homo sapiens
PREY
XRN2
RP11-227D2.1
5'-3' exoribonuclease 2
GO Process (7)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction framework for human mRNA degradation.
The degradation of mRNA is an important regulatory step in the control of gene expression. However, mammalian RNA decay pathways remain poorly characterized. To provide a framework for studying mammalian RNA decay, a two-hybrid protein interaction map was generated using 54 constructs from 38 human proteins predicted to function in mRNA decay. The results provide evidence for interactions between many ... [more]
Genome Res. Jul. 01, 2004; 14(7);1315-23 [Pubmed: 15231747]
Throughput
- High Throughput
Curated By
- BioGRID