BAIT
LSM7
YNL147W
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
GO Process (5)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
EXOSC8
CIP3, EAP2, OIP2, PCH1C, RRP43, Rrp43p, bA421P11.3, p9, RP11-421P11.3
exosome component 8
GO Process (5)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction framework for human mRNA degradation.
The degradation of mRNA is an important regulatory step in the control of gene expression. However, mammalian RNA decay pathways remain poorly characterized. To provide a framework for studying mammalian RNA decay, a two-hybrid protein interaction map was generated using 54 constructs from 38 human proteins predicted to function in mRNA decay. The results provide evidence for interactions between many ... [more]
Genome Res. Jul. 01, 2004; 14(7);1315-23 [Pubmed: 15231747]
Throughput
- High Throughput
Curated By
- BioGRID