Publication

Direct evidence that involucrin is a major early isopeptide cross-linked component of the keratinocyte cornified cell envelope.

Steinert PM, Marekov LN

Involucrin was the first protein to be identified as a likely constituent of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. However, to date, direct isolation from CEs of involucrin cross-linked by way of the transglutaminase-induced isopeptide bond has not been reported. We have treated human foreskin CEs with methanol/KOH (saponification) to hydrolyze off much of the lipids. ... [more]

Throughput

• Low Throughput

Curated By

• BioGRID