Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Characterization of a novel mammalian RGS protein that binds to Galpha proteins and inhibits pheromone signaling in yeast.

Chen C, Zheng B, Han J, Lin SC

Genetic studies of molecules that negatively regulate G-coupled receptor functions have led to the identification of a large gene family with an evolutionarily conserved domain, termed the RGS domain. It is now understood that RGS proteins serve as GTPase-activating proteins for subfamilies of the heterotrimeric G-proteins. We have isolated from mouse pituitary a full-length cDNA clone encoding a novel member ... [more]

J. Biol. Chem. Mar. 28, 1997; 272(13);8679-85 [Pubmed: 9079700]

Throughput

  • Low Throughput

Curated By

  • BioGRID