BAIT

PHF7

CG9576, Dmel\CG9576, Dmel_CG9576
PHD finger protein 7 ortholog
GO Process (1)
GO Function (1)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Drosophila melanogaster
PREY

CG1792

Dmel\CG1792, Dmel_CG1792
CG1792 gene product from transcript CG1792-RA
GO Process (0)
GO Function (1)
GO Component (0)

Gene Ontology Molecular Function

Drosophila melanogaster

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Transcription factor networks in Drosophila melanogaster.

Rhee DY, Cho DY, Zhai B, Slattery M, Ma L, Mintseris J, Wong CY, White KP, Celniker SE, Przytycka TM, Gygi SP, Obar RA, Artavanis-Tsakonas S

Specific cellular fates and functions depend on differential gene expression, which occurs primarily at the transcriptional level and is controlled by complex regulatory networks of transcription factors (TFs). TFs act through combinatorial interactions with other TFs, cofactors, and chromatin-remodeling proteins. Here, we define protein-protein interactions using a coaffinity purification/mass spectrometry method and study 459 Drosophila melanogaster transcription-related factors, representing approximately ... [more]

Cell Rep Sep. 25, 2014; 8(6);2031-43 [Pubmed: 25242320]

Quantitative Score

  • 17.763834 [HGSCore]

Throughput

  • High Throughput

Additional Notes

  • High confidence interactions were identified using a HyperGeometric Spectral Counts scoring method (HGSCore) and were filtered to a false discovery rate (FDR) of 2%.

Curated By

  • BioGRID