BAIT

SH3GL1

CNSA1, EEN, SH3D2B, SH3P8
SH3-domain GRB2-like 1
GO Process (2)
GO Function (2)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

The interaction between EEN and Abi-1, two MLL fusion partners, and synaptojanin and dynamin: implications for leukaemogenesis.

So CW, So CK, Cheung N, Chew SL, Sham MH, Chan LC

The mixed lineage leukaemia gene, MLL (also called HRX, ALL-1) in acute leukaemia is fused to at least 16 identified partner genes that display diverse structural and biochemical properties. Using GST pull down and the yeast two hybrid system, we show that two different MLL fusion partners with SH3 domains, EEN and Abi-1, interact with dynamin and synaptojanin, both of ... [more]

Leukemia Apr. 01, 2000; 14(4);594-601 [Pubmed: 10764144]

Throughput

  • Low Throughput

Curated By

  • BioGRID