NUTF2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
RAN
Gene Ontology Biological Process
- actin cytoskeleton organization [ISO]
- cellular protein complex localization [ISO]
- cellular protein localization [ISO]
- microtubule cytoskeleton organization [TAS]
- nucleocytoplasmic transport [TAS]
- positive regulation of protein binding [ISO]
- protein export from nucleus [ISO, TAS]
- protein import into nucleus [ISO, TAS]
- ribosomal large subunit export from nucleus [ISO]
- ribosomal small subunit export from nucleus [ISO]
- spermatid development [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.
Publication
The 1.6 angstroms resolution crystal structure of nuclear transport factor 2 (NTF2).
Nuclear transport factor 2 (NTF2) facilitates protein transport into the nucleus and interacts with both the small Ras-like GTPase Ran and nucleoporin p62. We have determined the structure of bacterially expressed rat NTF2 at 1.6 angstroms resolution using X-ray crystallography. The NTF2 polypeptide chain forms an alpha + beta barrel that opens at one end to form a distinctive hydrophobic ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID