BAIT

ELAV

44C11, 9F8A9, CG4262, Dmel\CG4262, EC7, EG:65F1.2, Elav-9F8A9, elav-1, elav-2, elav-3, fliJ, l(1)1Be, l(1)EC7, l(1)G0031, l(1)G0319, weg, Dmel_CG4262
embryonic lethal abnormal vision
GO Process (4)
GO Function (3)
GO Component (2)
Drosophila melanogaster
PREY

FNE

BEST:HL02010, BcDNA:HL02010, BcDNA:RE25290, CG4396, CR32646, Dmel\CG4396, Dmel_CR32646, MRE28, lincRNA.985, Dmel_CG4396
found in neurons
GO Process (2)
GO Function (2)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Drosophila melanogaster

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

The third RNA recognition motif of Drosophila ELAV protein has a role in multimerization.

Toba G, White K

ELAV is a neuron-specific RNA-binding protein in Drosophila that is required for development and maintenance of neurons. ELAV regulates alternative splicing of Neuroglian and erect wing (ewg) transcripts, and has been shown to form a multimeric complex on the last ewg intron. The protein has three RNA recognition motifs (RRM1, 2 and 3) with a hinge region between RRM2 and ... [more]

Nucleic Acids Res. Mar. 01, 2008; 36(4);1390-9 [Pubmed: 18203745]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
ELAV FNE
Phenotypic Suppression
Phenotypic Suppression

A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.

Low-FlyBase
-
ELAV FNE
Two-hybrid
Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

High-BioGRID
-
FNE ELAV
Two-hybrid
Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Low-FlyBase
-

Curated By