BAIT
NRXN1
Hs.22998, PTHSL2, SCZD17
neurexin 1
GO Process (38)
GO Function (9)
GO Component (6)
Gene Ontology Biological Process
- N-methyl-D-aspartate receptor clustering [ISS]
- adult behavior [IMP]
- angiogenesis [ISS]
- axon guidance [TAS]
- calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [ISS]
- cerebellar granule cell differentiation [ISS]
- establishment of protein localization [ISS]
- extracellular matrix organization [TAS]
- gamma-aminobutyric acid receptor clustering [ISS]
- gephyrin clustering [ISS]
- guanylate kinase-associated protein clustering [ISS]
- heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [ISS]
- learning [IMP]
- negative regulation of filopodium assembly [ISS]
- neuroligin clustering [ISS]
- neuromuscular process controlling balance [IMP, ISS]
- neuron cell-cell adhesion [ISS, TAS]
- neuronal signal transduction [TAS]
- neurotransmitter secretion [ISS]
- positive regulation of establishment of protein localization to plasma membrane [ISS]
- positive regulation of excitatory postsynaptic membrane potential [ISS]
- positive regulation of synapse assembly [ISS]
- positive regulation of synapse maturation [ISS]
- positive regulation of synaptic transmission, glutamatergic [ISS]
- postsynaptic density protein 95 clustering [ISS]
- postsynaptic membrane assembly [ISS]
- presynaptic membrane assembly [ISS]
- protein complex assembly involved in synapse maturation [ISS]
- protein localization to synapse [ISS]
- receptor localization to synapse [ISS]
- regulation of N-methyl-D-aspartate selective glutamate receptor activity [ISS]
- regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [ISS]
- social behavior [IMP]
- synapse assembly [ISS]
- synaptic transmission [ISS]
- synaptic vesicle clustering [ISS]
- vocal learning [IMP]
- vocalization behavior [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
NLGN2
neuroligin 2
GO Process (20)
GO Function (4)
GO Component (7)
Gene Ontology Biological Process
- cell-cell junction maintenance [NAS]
- gephyrin clustering [ISS]
- metabolic process [IBA]
- neuron cell-cell adhesion [IBA, ISS]
- positive regulation of excitatory postsynaptic membrane potential [ISS]
- positive regulation of inhibitory postsynaptic membrane potential [ISS]
- positive regulation of synapse assembly [ISS]
- positive regulation of synaptic transmission, GABAergic [ISS]
- positive regulation of synaptic transmission, glutamatergic [ISS]
- postsynaptic density protein 95 clustering [ISS]
- postsynaptic membrane assembly [ISS]
- presynaptic membrane assembly [ISS]
- protein localization to synapse [ISS]
- regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [ISS]
- regulation of respiratory gaseous exchange by neurological system process [ISS]
- regulation of synaptic transmission [IBA, ISS]
- single organismal cell-cell adhesion [NAS]
- synapse assembly [IBA, ISS, NAS]
- synapse organization [ISS]
- terminal button organization [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Structures, alternative splicing, and neurexin binding of multiple neuroligins.
Neuroligin 1 is a neuronal cell surface protein that binds to a subset of neurexins, polymorphic cell surface proteins that are also localized on neurons (Ichtchenko, K., Hata, Y., Nguyen, T., Ullrich, B., Missler, M., Moomaw, C., and Suedhof, T. C. (1995) Cell 81, 435-443). We now describe two novel neuroligins called neuroligins 2 and 3 that are similar in ... [more]
J. Biol. Chem. Feb. 02, 1996; 271(5);2676-82 [Pubmed: 8576240]
Throughput
- Low Throughput
Curated By
- BioGRID