BAIT
NRXN2
neurexin 2
GO Process (12)
GO Function (3)
GO Component (0)
Gene Ontology Biological Process
- adult behavior [IMP]
- gephyrin clustering [ISS]
- neuroligin clustering [ISS]
- neuron cell-cell adhesion [TAS]
- neurotransmitter secretion [ISS]
- postsynaptic density protein 95 clustering [ISS]
- postsynaptic membrane assembly [ISS]
- social behavior [IMP]
- synapse assembly [ISS]
- synaptic transmission [ISS]
- vocal learning [IMP]
- vocalization behavior [IMP]
Gene Ontology Molecular Function
Homo sapiens
PREY
NLGN2
neuroligin 2
GO Process (20)
GO Function (4)
GO Component (7)
Gene Ontology Biological Process
- cell-cell junction maintenance [NAS]
- gephyrin clustering [ISS]
- metabolic process [IBA]
- neuron cell-cell adhesion [IBA, ISS]
- positive regulation of excitatory postsynaptic membrane potential [ISS]
- positive regulation of inhibitory postsynaptic membrane potential [ISS]
- positive regulation of synapse assembly [ISS]
- positive regulation of synaptic transmission, GABAergic [ISS]
- positive regulation of synaptic transmission, glutamatergic [ISS]
- postsynaptic density protein 95 clustering [ISS]
- postsynaptic membrane assembly [ISS]
- presynaptic membrane assembly [ISS]
- protein localization to synapse [ISS]
- regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [ISS]
- regulation of respiratory gaseous exchange by neurological system process [ISS]
- regulation of synaptic transmission [IBA, ISS]
- single organismal cell-cell adhesion [NAS]
- synapse assembly [IBA, ISS, NAS]
- synapse organization [ISS]
- terminal button organization [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Structures, alternative splicing, and neurexin binding of multiple neuroligins.
Neuroligin 1 is a neuronal cell surface protein that binds to a subset of neurexins, polymorphic cell surface proteins that are also localized on neurons (Ichtchenko, K., Hata, Y., Nguyen, T., Ullrich, B., Missler, M., Moomaw, C., and Suedhof, T. C. (1995) Cell 81, 435-443). We now describe two novel neuroligins called neuroligins 2 and 3 that are similar in ... [more]
J. Biol. Chem. Feb. 02, 1996; 271(5);2676-82 [Pubmed: 8576240]
Throughput
- Low Throughput
Curated By
- BioGRID