BAIT
MYB
Cmyb, c-myb, c-myb_CDS, efg, RP1-32B1.1
v-myb avian myeloblastosis viral oncogene homolog
GO Process (10)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
- blood coagulation [TAS]
- chromatin remodeling [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- negative regulation of transcription, DNA-templated [IMP]
- positive regulation of T-helper cell differentiation [IMP]
- positive regulation of histone H3-K4 methylation [IMP]
- positive regulation of histone H3-K9 methylation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- positive regulation of transcription, DNA-templated [IMP, NAS]
- regulation of transcription, DNA-templated [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SND1
TDRD11, p100
staphylococcal nuclease and tudor domain containing 1
GO Process (1)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
The EVES motif mediates both intermolecular and intramolecular regulation of c-Myb.
The c-Myb transcription factor is a proto-oncoprotein whose latent transforming activity can be unmasked by truncation of either terminus. Because both ends of Myb are involved in negative regulation, we tested whether they could associate in a two-hybrid assay and identified a carboxy-terminal motif that interacts with the amino-terminal DNA-binding domain. The EVES motif is highly conserved in vertebrate c-Myb ... [more]
Genes Dev. Aug. 01, 1996; 10(15);1858-69 [Pubmed: 8756344]
Throughput
- Low Throughput
Related interactions
Curated By
- BioGRID