BAIT
HNRNPH1
HNRPH, HNRPH1, hnRNPH
heterogeneous nuclear ribonucleoprotein H1 (H)
GO Process (5)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CYR61
CCN1, GIG1, IGFBP10
cysteine-rich, angiogenic inducer, 61
GO Process (14)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- anatomical structure morphogenesis [TAS]
- cell adhesion [IBA]
- cell proliferation [TAS]
- cell-cell signaling [IBA]
- negative regulation of cell death [IBA]
- positive regulation of BMP signaling pathway [IGI]
- positive regulation of cell migration [IDA]
- positive regulation of osteoblast differentiation [IDA]
- positive regulation of osteoblast proliferation [IDA]
- positive regulation of protein kinase activity [IDA]
- positive regulation of protein phosphorylation [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of ERK1 and ERK2 cascade [IDA]
- wound healing, spreading of cells [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.
hnRNPs are polyvalent RNA binding proteins that have been implicated in a range of regulatory roles including splicing, mRNA decay, translation, and miRNA metabolism. A variety of genome wide studies have taken advantage of methods like CLIP and RIP to identify the targets and binding sites of RNA binding proteins. However, due to the complex nature of RNA-binding proteins, these ... [more]
RNA Biol Jan. 14, 2016; 13(4);400-11 [Pubmed: 26760575]
Throughput
- High Throughput
Additional Notes
- RIP-Seq
- iCLIP
Curated By
- BioGRID