BAIT
HNRNPH1
HNRPH, HNRPH1, hnRNPH
heterogeneous nuclear ribonucleoprotein H1 (H)
GO Process (5)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PTPRJ
CD148, DEP1, HPTPeta, R-PTP-ETA, SCC1
protein tyrosine phosphatase, receptor type, J
GO Process (17)
GO Function (9)
GO Component (8)
Gene Ontology Biological Process
- contact inhibition [NAS]
- negative regulation of MAP kinase activity [IDA]
- negative regulation of T cell receptor signaling pathway [IDA, IMP]
- negative regulation of cell growth [IDA]
- negative regulation of cell migration [IDA]
- negative regulation of cell proliferation [IDA]
- negative regulation of epidermal growth factor receptor signaling pathway [IMP]
- negative regulation of platelet-derived growth factor receptor signaling pathway [IDA]
- negative regulation of protein kinase B signaling [IMP]
- negative regulation of vascular permeability [IDA]
- peptidyl-tyrosine dephosphorylation [IDA, IMP]
- platelet-derived growth factor receptor signaling pathway [IMP]
- positive chemotaxis [IDA]
- positive regulation of cell adhesion [IMP]
- positive regulation of focal adhesion assembly [IMP]
- positive regulation of protein kinase B signaling [IMP]
- regulation of cell adhesion [IMP]
Gene Ontology Molecular Function- beta-catenin binding [IPI]
- delta-catenin binding [IPI]
- gamma-catenin binding [IPI]
- mitogen-activated protein kinase binding [IPI]
- phosphatase activity [IDA, IMP]
- platelet-derived growth factor receptor binding [IPI]
- protein binding [IPI]
- protein kinase binding [IPI]
- protein tyrosine phosphatase activity [IDA, IMP]
- beta-catenin binding [IPI]
- delta-catenin binding [IPI]
- gamma-catenin binding [IPI]
- mitogen-activated protein kinase binding [IPI]
- phosphatase activity [IDA, IMP]
- platelet-derived growth factor receptor binding [IPI]
- protein binding [IPI]
- protein kinase binding [IPI]
- protein tyrosine phosphatase activity [IDA, IMP]
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.
hnRNPs are polyvalent RNA binding proteins that have been implicated in a range of regulatory roles including splicing, mRNA decay, translation, and miRNA metabolism. A variety of genome wide studies have taken advantage of methods like CLIP and RIP to identify the targets and binding sites of RNA binding proteins. However, due to the complex nature of RNA-binding proteins, these ... [more]
RNA Biol Jan. 14, 2016; 13(4);400-11 [Pubmed: 26760575]
Throughput
- High Throughput
Additional Notes
- RIP-Seq
- iCLIP
Curated By
- BioGRID