BAIT
HNRNPH1
HNRPH, HNRPH1, hnRNPH
heterogeneous nuclear ribonucleoprotein H1 (H)
GO Process (5)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TAF1
BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, N-TAF1, NSCL2, OF, P250, TAF(II)250, TAF2A, TAFII-250, TAFII250, XDP
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
GO Process (15)
GO Function (10)
GO Component (3)
Gene Ontology Biological Process
- DNA-templated transcription, initiation [ISS]
- RNA polymerase II transcriptional preinitiation complex assembly [ISS]
- cellular response to DNA damage stimulus [IC]
- gene expression [TAS]
- histone acetylation [IDA]
- peptidyl-serine phosphorylation [IDA]
- peptidyl-threonine phosphorylation [IDA]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI]
- positive regulation of transcription initiation from RNA polymerase II promoter [ISS]
- protein autophosphorylation [IDA, TAS]
- transcription elongation from RNA polymerase II promoter [TAS]
- transcription from RNA polymerase II promoter [TAS]
- transcription initiation from RNA polymerase II promoter [TAS]
- viral process [TAS]
Gene Ontology Molecular Function- TBP-class protein binding [IPI]
- histone acetyltransferase activity [IDA]
- lysine-acetylated histone binding [IDA]
- p53 binding [IPI]
- protein binding [IPI]
- protein serine/threonine kinase activity [IDA]
- sequence-specific DNA binding [ISS]
- transcription coactivator activity [IDA]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [ISS]
- TBP-class protein binding [IPI]
- histone acetyltransferase activity [IDA]
- lysine-acetylated histone binding [IDA]
- p53 binding [IPI]
- protein binding [IPI]
- protein serine/threonine kinase activity [IDA]
- sequence-specific DNA binding [ISS]
- transcription coactivator activity [IDA]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [ISS]
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.
hnRNPs are polyvalent RNA binding proteins that have been implicated in a range of regulatory roles including splicing, mRNA decay, translation, and miRNA metabolism. A variety of genome wide studies have taken advantage of methods like CLIP and RIP to identify the targets and binding sites of RNA binding proteins. However, due to the complex nature of RNA-binding proteins, these ... [more]
RNA Biol Jan. 14, 2016; 13(4);400-11 [Pubmed: 26760575]
Throughput
- High Throughput
Additional Notes
- RIP-Seq
- iCLIP
Curated By
- BioGRID