BAIT
HNRNPH1
HNRPH, HNRPH1, hnRNPH
heterogeneous nuclear ribonucleoprotein H1 (H)
GO Process (5)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ITGB1BP1
ICAP-1A, ICAP-1B, ICAP-1alpha, ICAP1, ICAP1A, ICAP1B
integrin beta 1 binding protein 1
GO Process (34)
GO Function (5)
GO Component (12)
Gene Ontology Biological Process
- activation of protein kinase B activity [IDA]
- blood vessel endothelial cell proliferation involved in sprouting angiogenesis [IDA]
- cell migration [TAS]
- cell-matrix adhesion [IDA]
- cellular response to fibroblast growth factor stimulus [IDA]
- cellular response to vascular endothelial growth factor stimulus [IDA]
- integrin activation [ISS]
- integrin-mediated signaling pathway [IDA]
- intracellular signal transduction [TAS]
- myoblast migration [ISS]
- negative regulation of ERK1 and ERK2 cascade [IDA]
- negative regulation of cell adhesion involved in substrate-bound cell migration [ISS]
- negative regulation of cell migration involved in sprouting angiogenesis [IDA]
- negative regulation of cell proliferation [IDA]
- negative regulation of fibroblast migration [ISS]
- negative regulation of focal adhesion assembly [IDA]
- negative regulation of protein binding [IDA]
- negative regulation of protein kinase activity [IDA]
- negative regulation of protein targeting to membrane [IDA]
- negative regulation of substrate adhesion-dependent cell spreading [IDA]
- positive regulation of Notch signaling pathway [IDA]
- positive regulation of cell proliferation [IDA]
- positive regulation of endothelial cell migration [IDA]
- positive regulation of protein kinase B signaling [IDA]
- positive regulation of protein targeting to membrane [ISS]
- positive regulation of stress fiber assembly [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- protein transport [IDA]
- receptor clustering [ISS]
- regulation of Cdc42 GTPase activity [IDA]
- regulation of blood vessel size [IDA]
- regulation of cell adhesion mediated by integrin [ISS]
- regulation of integrin-mediated signaling pathway [ISS]
- tube formation [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.
hnRNPs are polyvalent RNA binding proteins that have been implicated in a range of regulatory roles including splicing, mRNA decay, translation, and miRNA metabolism. A variety of genome wide studies have taken advantage of methods like CLIP and RIP to identify the targets and binding sites of RNA binding proteins. However, due to the complex nature of RNA-binding proteins, these ... [more]
RNA Biol Jan. 14, 2016; 13(4);400-11 [Pubmed: 26760575]
Throughput
- High Throughput
Additional Notes
- RIP-Seq
- iCLIP
Curated By
- BioGRID