BAIT
HNRNPH1
HNRPH, HNRPH1, hnRNPH
heterogeneous nuclear ribonucleoprotein H1 (H)
GO Process (5)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CLCF1
BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6
cardiotrophin-like cytokine factor 1
GO Process (11)
GO Function (6)
GO Component (4)
Gene Ontology Biological Process
- B cell differentiation [ISS]
- JAK-STAT cascade [ISS]
- cell surface receptor signaling pathway [ISS]
- cytokine-mediated signaling pathway [NAS]
- negative regulation of neuron apoptotic process [IDA]
- positive regulation of B cell proliferation [ISS]
- positive regulation of astrocyte differentiation [ISS]
- positive regulation of cell proliferation [IDA]
- positive regulation of immunoglobulin production [ISS]
- positive regulation of isotype switching to IgE isotypes [ISS]
- positive regulation of tyrosine phosphorylation of Stat3 protein [IDA, TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.
hnRNPs are polyvalent RNA binding proteins that have been implicated in a range of regulatory roles including splicing, mRNA decay, translation, and miRNA metabolism. A variety of genome wide studies have taken advantage of methods like CLIP and RIP to identify the targets and binding sites of RNA binding proteins. However, due to the complex nature of RNA-binding proteins, these ... [more]
RNA Biol Jan. 14, 2016; 13(4);400-11 [Pubmed: 26760575]
Throughput
- High Throughput
Additional Notes
- RIP-Seq
- iCLIP
Curated By
- BioGRID