BAIT
HNRNPH1
HNRPH, HNRPH1, hnRNPH
heterogeneous nuclear ribonucleoprotein H1 (H)
GO Process (5)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
MLXIPL
CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH, bHLHd14
MLX interacting protein-like
GO Process (24)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- anatomical structure morphogenesis [TAS]
- cellular response to carbohydrate stimulus [IBA]
- energy reserve metabolic process [TAS]
- fatty acid homeostasis [ISS]
- glucose homeostasis [ISS]
- glucose mediated signaling pathway [ISS]
- intracellular signal transduction [TAS]
- negative regulation of cell cycle arrest [IMP]
- negative regulation of oxidative phosphorylation [IMP]
- negative regulation of peptidyl-serine phosphorylation [IMP]
- negative regulation of transcription, DNA-templated [ISS]
- positive regulation of cell proliferation [IMP]
- positive regulation of cellular metabolic process [TAS]
- positive regulation of fatty acid biosynthetic process [ISS]
- positive regulation of glycolytic process [IMP]
- positive regulation of lipid biosynthetic process [IMP]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- positive regulation of transcription, DNA-templated [ISS]
- regulation of energy homeostasis [ISS]
- regulation of fatty acid biosynthetic process [TAS]
- regulation of transcription from RNA polymerase II promoter [IBA]
- regulation of transcription, DNA-templated [NAS]
- small molecule metabolic process [TAS]
- triglyceride homeostasis [NAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.
hnRNPs are polyvalent RNA binding proteins that have been implicated in a range of regulatory roles including splicing, mRNA decay, translation, and miRNA metabolism. A variety of genome wide studies have taken advantage of methods like CLIP and RIP to identify the targets and binding sites of RNA binding proteins. However, due to the complex nature of RNA-binding proteins, these ... [more]
RNA Biol Jan. 14, 2016; 13(4);400-11 [Pubmed: 26760575]
Throughput
- High Throughput
Additional Notes
- RIP-Seq
- iCLIP
Curated By
- BioGRID