BAIT
MYOZ1
CS-2, FATZ, MYOZ
myozenin 1
GO Process (1)
GO Function (2)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
ACTN2
CMD1AA
actinin, alpha 2
GO Process (16)
GO Function (10)
GO Component (11)
Gene Ontology Biological Process
- blood coagulation [TAS]
- cell adhesion [TAS]
- focal adhesion assembly [IMP]
- microspike assembly [IDA]
- muscle filament sliding [TAS]
- negative regulation of potassium ion transmembrane transporter activity [IMP]
- negative regulation of potassium ion transport [IMP]
- negative regulation of protein localization to cell surface [IMP]
- platelet activation [TAS]
- platelet degranulation [TAS]
- positive regulation of potassium ion transmembrane transporter activity [IDA]
- positive regulation of potassium ion transport [IDA]
- protein homotetramerization [IDA]
- regulation of apoptotic process [NAS]
- regulation of membrane potential [IMP]
- synaptic transmission [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
FATZ, a filamin-, actinin-, and telethonin-binding protein of the Z-disc of skeletal muscle.
We report the identification and characterization of a novel 32-kDa protein expressed in skeletal muscle and located in the Z-disc of the sarcomere. We found that this protein binds to three other Z-disc proteins; therefore, we have named it FATZ, gamma-filamin/ABP-L, alpha-actinin and telethonin binding protein of the Z-disc. From yeast two-hybrid experiments we are able to show that the ... [more]
J. Biol. Chem. Dec. 29, 2000; 275(52);41234-42 [Pubmed: 10984498]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ACTN2 MYOZ1 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | - |
Curated By
- BioGRID