Interaction directly demonstrated at the atomic level by X-ray crystallography. Also used for NMR or Electron Microscopy (EM) structures. If there is no obvious bait-hit directionality to the interaction involving 3 or more proteins, then the co-crystallized proteins should be listed as a complex.

Publication

Crystal structure of human mitochondrial single-stranded DNA binding protein at 2.4 A resolution.

Yang C, Curth U, Urbanke C, Kang C

We solved the crystal structure of the homotetrameric single-stranded DNA binding (SSB) protein from human mitochondria at a resolution of 2.4 A. The tetramer is formed by two dimers interacting head-to-head and shows D2 symmetry. Sequence-related tetrameric SSB proteins occur in prokaryotes and eukaryotic mitochondria; this is the first report of an atomic resolution structure of this type of protein. ... [more]

Nat. Struct. Biol. Feb. 01, 1997; 4(2);153-7 [Pubmed: 9033597]

Throughput

Low Throughput

Curated By

BioGRID

Interaction Summary

SSBP1

Gene Ontology Biological Process

Gene Ontology Molecular Function

chromatin binding [IDA]poly(A) RNA binding [IDA]protein binding [IPI]

Gene Ontology Cellular Component