BAIT
RASA1
CM-AVM, CMAVM, GAP, PKWS, RASA, RASGAP, p120GAP, p120RASGAP
RAS p21 protein activator (GTPase activating protein) 1
GO Process (14)
GO Function (6)
GO Component (3)
Gene Ontology Biological Process
- blood vessel morphogenesis [IMP]
- embryo development [ISS]
- intracellular signal transduction [NAS]
- mitotic cytokinesis [ISS]
- negative regulation of Ras protein signal transduction [IBA]
- negative regulation of cell adhesion [IDA]
- negative regulation of cell-matrix adhesion [IDA]
- negative regulation of neuron apoptotic process [ISS]
- positive regulation of Ras GTPase activity [IBA]
- regulation of RNA metabolic process [NAS]
- regulation of actin filament polymerization [IDA]
- regulation of cell shape [NAS]
- signal transduction [IDA]
- vasculogenesis [ISS]
Gene Ontology Molecular Function
Homo sapiens
PREY
ANXA6
ANX6, CBP68
annexin A6
GO Process (2)
GO Function (8)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Far Western
An interaction is detected between a protein immobilized on a membrane and a purified protein probe.
Publication
Mapping the site of interaction between annexin VI and the p120GAP C2 domain.
Annexin VI is a Ca(2+)-dependent membrane and phospholipid binding protein. It mediates a protein-protein interaction with the Ras p21 regulatory protein p120GAP. In this study we have mapped the binding site of GAP within the annexin VI protein. Using Far Western overlay binding assays and cell lysate competition studies we have mapped the site of interaction to the inter-lobe linker ... [more]
FEBS Lett. Oct. 22, 1999; 460(1);166-72 [Pubmed: 10571081]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| RASA1 ANXA6 | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - |
Curated By
- BioGRID