BAIT

WBP4

FBP21
WW domain binding protein 4
GO Process (1)
GO Function (2)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

ZC2HC1A

C8orf70, FAM164A, CGI-62
zinc finger, C2HC-type containing 1A
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

A new role for FBP21 as regulator of Brr2 helicase activity.

Henning LM, Santos KF, Sticht J, Jehle S, Lee CT, Wittwer M, Urlaub H, Stelzl U, Wahl MC, Freund C

Splicing of eukaryotic pre-mRNA is carried out by the spliceosome, which assembles stepwise on each splicing substrate. This requires the concerted action of snRNPs and non-snRNP accessory proteins, the functions of which are often not well understood. Of special interest are B complex factors that enter the spliceosome prior to catalytic activation and may alter splicing kinetics and splice site ... [more]

Nucleic Acids Res. Jul. 27, 2017; 45(13);7922-7937 [Pubmed: 28838205]

Throughput

  • Low Throughput

Curated By

  • BioGRID