BAIT

NDN

HsT16328, PWCR
necdin, melanoma antigen (MAGE) family member
UPS Project
GO Process (2)
GO Function (0)
GO Component (0)

Gene Ontology Biological Process

Homo sapiens
PREY

CCT3

CCT-gamma, CCTG, PIG48, TCP-1-gamma, TRIC5, RP11-443G18.6
chaperonin containing TCP1, subunit 3 (gamma)
GO Process (3)
GO Function (2)
GO Component (6)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Proximity Label-MS

An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.

Publication

The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.

Sanderson MR, Badior KE, Fahlman RP, Wevrick R

Prader-Willi syndrome (PWS) is a neurodevelopmental disorder caused by the loss of function of a set of imprinted genes on chromosome 15q11-15q13. One of these genes, NDN, encodes necdin, a protein that is important for neuronal differentiation and survival. Loss of Ndn in mice causes defects in the formation and function of the nervous system. Necdin is a member of ... [more]

Hum Genet Dec. 01, 2020; 139(12);1513-1529 [Pubmed: 32529326]

Throughput

  • High Throughput

Curated By

  • BioGRID