BAIT
CD59
16.3A5, 1F5, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20
CD59 molecule, complement regulatory protein
GO Process (5)
GO Function (2)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
C9
ARMD15, C9D
complement component 9
GO Process (3)
GO Function (0)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Identity of a peptide domain of human C9 that is bound by the cell-surface complement inhibitor, CD59.
The CD59 antigen is a plasma membrane glycoprotein that serves as an inhibitor of the C5b-9 complex of complement. This inhibitory activity appears related to the capacity of CD59 to bind with high affinity to sites that are nascently exposed in the alpha-chain subunit of human C8, as well as within the C9b domain (amino acid residues 245-538) of human ... [more]
J. Biol. Chem. Oct. 21, 1994; 269(42);26424-30 [Pubmed: 7523406]
Throughput
- Low Throughput
Related interactions
Curated By
- BioGRID