BAIT

RNF183

5830442J12Rik, RP24-189G18.1
ring finger protein 183
GO Process (0)
GO Function (0)
GO Component (0)
Mus musculus
PREY

HDLBP

HBP, PRO2900, VGL
high density lipoprotein binding protein
GO Process (0)
GO Function (3)
GO Component (2)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Proximity Label-MS

An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.

Publication

Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its ?1 subunit.

Okamoto T, Wu Y, Matsuhisa K, Saito A, Sakaue F, Imaizumi K, Kaneko M

We previously reported that RNF183, a member of the RING finger (RNF) protein family, is specifically expressed in the renal collecting duct and that RNF183 mRNA is induced by the activity of nuclear factor of activated T cells 5 (NFAT5), which regulates the transcription of essential proteins for adaptation to hypertonic conditions. The renal medulla is the only tissue that ... [more]

Biochem Biophys Res Commun Dec. 22, 2019; 521(4);1030-1035 [Pubmed: 31732153]

Throughput

  • High Throughput

Curated By

  • BioGRID