BAIT
ODF2
AI848335, MMTEST29, RP23-443G7.4
outer dense fiber of sperm tails 2
GO Process (1)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
HSPA1A
HSP72, Hsp70-1, Hspa1, Hspa1b
heat shock 70kD protein 1A
GO Process (24)
GO Function (15)
GO Component (22)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- DNA repair [ISO]
- binding of sperm to zona pellucida [ISO]
- cellular heat acclimation [ISO]
- cellular response to heat [ISO]
- defense response [IDA]
- mRNA catabolic process [ISO, ISS]
- negative regulation of apoptotic process [IDA, ISO]
- negative regulation of cell death [ISO]
- negative regulation of cell growth [ISO, ISS]
- negative regulation of cell proliferation [ISO, ISS]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IDA, ISO]
- negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [ISO]
- negative regulation of inclusion body assembly [ISO]
- negative regulation of myeloid cell apoptotic process [IDA]
- negative regulation of protein ubiquitination [ISO]
- negative regulation of vasoconstriction [IMP]
- positive regulation of T cell mediated cytotoxicity [IDA]
- positive regulation of erythrocyte differentiation [ISO]
- protein refolding [ISO]
- regulation of cell death [ISO]
- response to heat [ISO]
- response to unfolded protein [IMP, ISO, ISS]
- telomere maintenance [ISO]
Gene Ontology Molecular Function- ATP binding [ISO]
- ATPase activity [ISO]
- ATPase activity, coupled [ISO]
- G-protein coupled receptor binding [ISO]
- NF-kappaB binding [IPI]
- double-stranded RNA binding [ISO]
- enzyme binding [ISO]
- heat shock protein binding [ISO]
- poly(A) RNA binding [ISO]
- protease binding [IPI]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein binding involved in protein folding [ISO]
- ubiquitin protein ligase binding [ISO]
- unfolded protein binding [ISO]
- ATP binding [ISO]
- ATPase activity [ISO]
- ATPase activity, coupled [ISO]
- G-protein coupled receptor binding [ISO]
- NF-kappaB binding [IPI]
- double-stranded RNA binding [ISO]
- enzyme binding [ISO]
- heat shock protein binding [ISO]
- poly(A) RNA binding [ISO]
- protease binding [IPI]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein binding involved in protein folding [ISO]
- ubiquitin protein ligase binding [ISO]
- unfolded protein binding [ISO]
Gene Ontology Cellular Component
- COP9 signalosome [ISO]
- aggresome [ISO]
- apical plasma membrane [IDA]
- basolateral plasma membrane [IDA]
- blood microparticle [ISO]
- cell body [ISO]
- centriole [ISO]
- cytoplasm [ISO, ISS]
- cytosol [IDA, ISO]
- extracellular vesicular exosome [ISO]
- focal adhesion [ISO]
- inclusion body [ISO]
- intracellular [ISO]
- mitochondrion [ISO]
- nuclear speck [ISO, ISS]
- nucleus [IDA, ISO, ISS]
- perinuclear region of cytoplasm [ISO, ISS]
- protein complex [IDA]
- ribonucleoprotein complex [ISO]
- ubiquitin ligase complex [ISO]
- vesicle [ISO]
- zona pellucida receptor complex [ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The novel testicular enrichment protein Cfap58 is required for Notch-associated ciliogenesis.
Cilia and flagella are critical organelles with conserved internal structures and diverse developmental and physiological processes according to cell type. Although the core components of structures are shared with thousands of associated proteins involved in cilia or flagella formation, we hypothesized that some unknown proteins, such as outer dense fiber 2 (Odf2/Cenexin) perform distinct functions in these organelles. In the ... [more]
Biosci Rep Dec. 31, 2019; 40(1); [Pubmed: 31904090]
Throughput
- High Throughput
Curated By
- BioGRID